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ARG1 Full-Length MS Protein Standard

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Product Description


NameARG1 Full-Length MS Protein Standard
Cat#CPFL304649
Protein Namearginase 1
SymbolARG1
SynonymsOTTHUMP00000017209; arginase 1; liver-type arginase; type I arginase; arginase, liver
AccessionNM_000045
Cytogenetic6q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionARG1 Full-Length MS Protein Standard (NP_000036), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

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