BCL2 Full-Length MS Protein Standard


Product Description:

Name BCL2 Full-Length MS Protein Standard
Cat# CPFL304498
Protein NameB-Cell CLL/Lymphoma 2
SymbolBCL2
SynonymsBcl-2; PPP1R50
AccessionNM_000633
Cytogenetic18q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW26.1 kDa
Expression TrueORF CloneRC204498
DescriptionBCL2 Full-Length MS Protein Standard (NP_000624), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.

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