TGM1 Full-Length MS Protein Standard


Product Description:

Name TGM1 Full-Length MS Protein Standard
Cat# CPFL304492
Protein Nametransglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
SymbolTGM1
SynonymsARCI1; ICR2; KTG; LI; LI1; TGASE; TGK
AccessionNM_000359
Cytogenetic14q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW89.6 kDa
Expression TrueORF CloneRC204492
DescriptionTGM1 Full-Length MS Protein Standard (NP_000350), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3 UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).

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