MAP2K6 Full-Length MS Protein Standard


Product Description:

Name MAP2K6 Full-Length MS Protein Standard
Cat# CPFL304481
Protein Namemitogen-activated protein kinase kinase 6
SymbolMAP2K6
SynonymsMAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3
AccessionNM_002758
Cytogenetic17q24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW37.3 kDa
Expression TrueORF CloneRC204481
DescriptionMAP2K6 Full-Length MS Protein Standard (NP_002749), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

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