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GNS Full-Length MS Protein Standard

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Product Description


NameGNS Full-Length MS Protein Standard
Cat#CPFL304458
Protein Nameglucosamine (N-acetyl)-6-sulfatase
SymbolGNS
SynonymsG6S
AccessionNM_002076
Cytogenetic12q14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGNS Full-Length MS Protein Standard (NP_002067), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

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