SEC62 Full-Length MS Protein Standard


Product Description:

Name SEC62 Full-Length MS Protein Standard
Cat# CPFL304452
Protein NameSEC62 homolog (S. cerevisiae)
SymbolSEC62
SynonymsDtrp1; HTP1; TLOC1; TP-1
AccessionNM_003262
Cytogenetic3q26.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW45.7 kDa
Expression TrueORF CloneRC204452
DescriptionSEC62 Full-Length MS Protein Standard (NP_003253), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

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