CALML5 Full-Length MS Protein Standard


Product Description:

Name CALML5 Full-Length MS Protein Standard
Cat# CPFL304372
Protein NameCalmodulin-like 5
SymbolCALML5
SynonymsCLSP
AccessionNM_017422
Cytogenetic10p15.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW15.7 kDa
Expression TrueORF CloneRC204372
DescriptionCALML5 Full-Length MS Protein Standard (NP_059118), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.

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