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MRPL19 Full-Length MS Protein Standard

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Product Description


NameMRPL19 Full-Length MS Protein Standard
Cat#CPFL304329
Protein Namemitochondrial ribosomal protein L19
SymbolMRPL19
SynonymsL19mt; MRP-L15; MRP-L19; MRPL15; RLX1; RPML15
AccessionNM_014763
Cytogenetic2p11.1-q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMRPL19 Full-Length MS Protein Standard (NP_055578), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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