CRLF3 Full-Length MS Protein Standard


Product Description:

Name CRLF3 Full-Length MS Protein Standard
Cat# CPFL304326
Protein Namecytokine receptor-like factor 3
SymbolCRLF3
SynonymsCREME-9; CREME9; CRLM9; CYTOR4; FRWS; p48.2
AccessionNM_015986
Cytogenetic17q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW49.6 kDa
Expression TrueORF CloneRC204326
DescriptionCRLF3 Full-Length MS Protein Standard (NP_057070), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.

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