GUSB Full-Length MS Protein Standard


Product Description:

Name GUSB Full-Length MS Protein Standard
Cat# CPFL304325
Protein Nameglucuronidase, beta
SymbolGUSB
SynonymsBG; MPS7
AccessionNM_000181
Cytogenetic7q21.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW72.5 kDa
Expression TrueORF CloneRC204325
DescriptionGUSB Full-Length MS Protein Standard (NP_000172), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

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