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MMAB Full-Length MS Protein Standard

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Product Description


NameMMAB Full-Length MS Protein Standard
Cat#CPFL304290
Protein Namemethylmalonic aciduria (cobalamin deficiency) cblB type
SymbolMMAB
SynonymsATR; cblB; CFAP23; cob
AccessionNM_052845
Cytogenetic12q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMMAB Full-Length MS Protein Standard (NP_443077), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.

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