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GMPS Full-Length MS Protein Standard

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Product Description


NameGMPS Full-Length MS Protein Standard
Cat#CPFL304267
Protein Nameguanine monphosphate synthetase
SymbolGMPS
SynonymsMLL/GMPS fusion protein; GMP synthase; GMP synthetase; glutamine amidotransferase; guanine monophosphate synthetase; guanosine 5-monophosphate synthase; guanine monphosphate synthetase
AccessionNM_003875
Cytogenetic3q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGMPS Full-Length MS Protein Standard (NP_003866), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

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