> 80% as determined by SDS-PAGE and Coomassie blue staining
Human HEK293 cells
Expression TrueORF Clone
NT5C Full-Length MS Protein Standard (NP_055410), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5 deoxyribonucleotides (dNTP) and 2(3)-dNTP and ribonucleotides, but not 5 ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.