TCL1A Full-Length MS Protein Standard

Product Information
Protein Name
T-cell leukemia/lymphoma 1A
Description
TCL1A Full-Length MS Protein Standard (NP_068801), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 )
Symbol
TCL1A
Synonyms
TCL1
Accession
NM_021966
Cytogenetic
14q32.1
Amino Acid Labeled
[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression Host
Human HEK293 cells
Predicted MW
13.3 kDa
Expression True or False Clone
RC204243
Protein Sequence
>RC204243 representing NM_021966
MAECPTLGEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVLLRREDVVLGRPMTPTQIGPS
LLPIMWQLYPDGRYRSSDSSFWRLVYHIKIDGVEDML

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