DNAJA3 Full-Length MS Protein Standard


Product Description:

Name DNAJA3 Full-Length MS Protein Standard
Cat# CPFL304240
Protein NameDnaJ (Hsp40) homolog, subfamily A, member 3
SymbolDNAJA3
SynonymsHCA57; hTID-1; TID1
AccessionNM_005147
Cytogenetic16p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW52.3 kDa
Expression TrueORF CloneRC204240
DescriptionDNAJA3 Full-Length MS Protein Standard (NP_005138), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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