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JUP Full-Length MS Protein Standard

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Product Description


NameJUP Full-Length MS Protein Standard
Cat#CPFL304209
Protein Namejunction plakoglobin
SymbolJUP
SynonymsARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
AccessionNM_002230
Cytogenetic17q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionJUP Full-Length MS Protein Standard (NP_002221), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

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