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DTNBP1 Full-Length MS Protein Standard

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Product Description


NameDTNBP1 Full-Length MS Protein Standard
Cat#CPFL304208
Protein Namedystrobrevin binding protein 1
SymbolDTNBP1
SynonymsBLOC1S8; DBND; HPS7; My031; SDY
AccessionNM_032122
Cytogenetic6p22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDTNBP1 Full-Length MS Protein Standard (NP_115498), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

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