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DPH3 Full-Length MS Protein Standard

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Product Description


NameDPH3 Full-Length MS Protein Standard
Cat#CPFL304203
Protein NameDPH3, KTI11 homolog (S. cerevisiae)
SymbolDPH3
SynonymsDELGIP; DELGIP1; DESR1; DPH3A; KTI11; ZCSL2
AccessionNM_206831
Cytogenetic3p25.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDPH3 Full-Length MS Protein Standard (NP_996662), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform.

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