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UBE2A Full-Length MS Protein Standard

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Product Description


NameUBE2A Full-Length MS Protein Standard
Cat#CPFL304194
Protein Nameubiquitin-conjugating enzyme E2A
SymbolUBE2A
SynonymsHHR6A; MRXS30; MRXSN; RAD6A; UBC2
AccessionNM_003336
CytogeneticXq24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionUBE2A Full-Length MS Protein Standard (NP_003327), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

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