| Name | BTD Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL304153 |
| Protein Name | biotinidase |
| Symbol | BTD |
| Synonyms | biotinidase |
| Accession | NM_000060 |
| Cytogenetic | 3p25 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 56.7 kDa |
| Expression TrueORF Clone | RC204153 |
| Description | BTD Full-Length MS Protein Standard (NP_000051), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described. |
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