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GBE1 Full-Length MS Protein Standard

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Product Description


NameGBE1 Full-Length MS Protein Standard
Cat#CPFL304152
Protein Nameglucan (1,4-alpha-), branching enzyme 1
SymbolGBE1
SynonymsAPBD; GBE; GSD4
AccessionNM_000158
Cytogenetic3p12.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGBE1 Full-Length MS Protein Standard (NP_000149), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersens disease).

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