|Name||CD99 Full-Length MS Protein Standard|
|Protein Name||CD99 molecule|
|Synonyms||HBA71; MIC2; MIC2X; MIC2Y; MSK5X|
|Cytogenetic||Xp22.32 and Yp11.3|
|Amino Acid Labeled||[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys|
|Description||CD99 Full-Length MS Protein Standard (NP_002405), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. Cyclophilin A binds to CD99 and may act as a signaling regulator of CD99. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. Three transcript variants encoding different isoforms have been found for this gene.|
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