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COTL1 Full-Length MS Protein Standard

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Product Description


NameCOTL1 Full-Length MS Protein Standard
Cat#CPFL304055
Protein Namecoactosin-like 1 (Dictyostelium)
SymbolCOTL1
SynonymsCLP
AccessionNM_021149
Cytogenetic16q24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCOTL1 Full-Length MS Protein Standard (NP_066972), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

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