XRCC6 Full-Length MS Protein Standard


Product Description:

Name XRCC6 Full-Length MS Protein Standard
Cat# CPFL304048
Protein NameX-ray repair complementing defective repair in Chinese hamster cells 6
SymbolXRCC6
SynonymsCTC75; CTCBF; G22P1; KU70; ML8; TLAA
AccessionNM_001469
Cytogenetic22q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW69.7 kDa
Expression TrueORF CloneRC204048
DescriptionXRCC6 Full-Length MS Protein Standard (NP_001460), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

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