UBQLN1 Full-Length MS Protein Standard


Product Description:

Name UBQLN1 Full-Length MS Protein Standard
Cat# CPFL304020
Protein Nameubiquilin 1
SymbolUBQLN1
SynonymsDA41; DSK2; PLIC-1; UBQN; XDRP1
AccessionNM_053067
Cytogenetic9q22|9q21.2-q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW59 kDa
Expression TrueORF CloneRC204020
DescriptionUBQLN1 Full-Length MS Protein Standard (NP_444295), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimers and Parkinsons disease. Two transcript variants encoding different isoforms have been found for this gene.

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