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GADD45A Full-Length MS Protein Standard

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Product Description


NameGADD45A Full-Length MS Protein Standard
Cat#CPFL304005
Protein Namegrowth arrest and DNA-damage-inducible, alpha
SymbolGADD45A
SynonymsDDIT1; GADD45
AccessionNM_001924
Cytogenetic1p31.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGADD45A Full-Length MS Protein Standard (NP_001915), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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