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ASIC4 Full-Length MS Protein Standard

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Product Description


NameASIC4 Full-Length MS Protein Standard
Cat#CPFL303827
Protein Nameacid-sensing (proton-gated) ion channel family member 4
SymbolASIC4
SynonymsACCN4; BNAC4
AccessionNM_182847
Cytogenetic2q35
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionACCN4 Full-Length MS Protein Standard (NP_878267), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.

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