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CDH11 Full-Length MS Protein Standard

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Product Description


NameCDH11 Full-Length MS Protein Standard
Cat#CPFL303810
Protein Namecadherin 11, type 2, OB-cadherin (osteoblast)
SymbolCDH11
SynonymsCAD11; CDHOB; OB; OSF-4
AccessionNM_001797
Cytogenetic16q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCDH11 Full-Length MS Protein Standard (NP_001788), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

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