NTRK3 Full-Length MS Protein Standard


Product Description:

Name NTRK3 Full-Length MS Protein Standard
Cat# CPFL303781
Protein Nameneurotrophic tyrosine kinase, receptor, type 3
SymbolNTRK3
Synonymsgp145(trkC); TRKC
AccessionNM_001007156
Cytogenetic15q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW64.9 kDa
Expression TrueORF CloneRC203781
DescriptionNTRK3 Full-Length MS Protein Standard (NP_001007157), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

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