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MAT1A Full-Length MS Protein Standard

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Product Description


NameMAT1A Full-Length MS Protein Standard
Cat#CPFL303765
Protein Namemethionine adenosyltransferase I, alpha
SymbolMAT1A
SynonymsMAT; MATA1; SAMS; SAMS1
AccessionNM_000429
Cytogenetic10q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMAT1A Full-Length MS Protein Standard (NP_000420), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

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