TRIM25 Full-Length MS Protein Standard


Product Description:

Name TRIM25 Full-Length MS Protein Standard
Cat# CPFL303757
Protein Nametripartite motif containing 25
SymbolTRIM25
SynonymsEFP; RNF147; Z147; ZNF147
AccessionNM_005082
Cytogenetic17q23.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW70.8 kDa
Expression TrueORF CloneRC203757
DescriptionTRIM25 Full-Length MS Protein Standard (NP_005073), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

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