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LMBR1 Full-Length MS Protein Standard

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Product Description


NameLMBR1 Full-Length MS Protein Standard
Cat#CPFL303703
Protein Namelimb region 1 homolog (mouse)
SymbolLMBR1
SynonymsACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS
AccessionNM_022458
Cytogenetic7q36
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionLMBR1 Full-Length MS Protein Standard (NP_071903), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

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