HNRNPLL Full-Length MS Protein Standard


Product Description:

Name HNRNPLL Full-Length MS Protein Standard
Cat# CPFL303569
Protein Nameheterogeneous nuclear ribonucleoprotein L
SymbolHNRNPLL
SynonymsHNRPLL; SRRF
AccessionNM_138394
Cytogenetic2p22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW59.9 kDa
Expression TrueORF CloneRC203569
DescriptionHNRPLL Full-Length MS Protein Standard (NP_612403), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 )

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