IRF1 Full-Length MS Protein Standard


Product Description:

Name IRF1 Full-Length MS Protein Standard
Cat# CPFL303500
Protein Nameinterferon regulatory factor 1
SymbolIRF1
SynonymsIRF-1; MAR
AccessionNM_002198
Cytogenetic5q31.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW36.3 kDa
Expression TrueORF CloneRC203500
DescriptionIRF1 Full-Length MS Protein Standard (NP_002189), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

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