ARHGDIB Full-Length MS Protein Standard


Product Description:

Name ARHGDIB Full-Length MS Protein Standard
Cat# CPFL303496
Protein NameRho GDP dissociation inhibitor (GDI) beta
SymbolARHGDIB
SynonymsD4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
AccessionNM_001175
Cytogenetic12p12.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW22.8 kDa
Expression TrueORF CloneRC203496
DescriptionARHGDIB Full-Length MS Protein Standard (NP_001166), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 )

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