COPS4 Full-Length MS Protein Standard


Product Description:

Name COPS4 Full-Length MS Protein Standard
Cat# CPFL303441
Protein NameCOP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
SymbolCOPS4
SynonymsCSN4
AccessionNM_016129
Cytogenetic4q21.22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.1 kDa
Expression TrueORF CloneRC203441
DescriptionCOPS4 Full-Length MS Protein Standard (NP_057213), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes one of eight subunits composing COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Two transcript variants encoding different isoforms have been found for this gene.

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