BRMS1 Full-Length MS Protein Standard


Product Description:

Name BRMS1 Full-Length MS Protein Standard
Cat# CPFL303428
Protein Namebreast cancer metastasis suppressor 1
SymbolBRMS1
SynonymsDKFZp564A063
AccessionNM_015399
Cytogenetic11q13-q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW28.3 kDa
Expression TrueORF CloneRC203428
DescriptionBRMS1 Full-Length MS Protein Standard (NP_056214), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

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