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NPM1 Full-Length MS Protein Standard

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Product Description


NameNPM1 Full-Length MS Protein Standard
Cat#CPFL303344
Protein Namenucleophosmin (nucleolar phosphoprotein B23, numatrin)
SymbolNPM1
SynonymsB23; NPM
AccessionNM_002520
Cytogenetic5q35.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNPM1 Full-Length MS Protein Standard (NP_002511), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

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