UBE2B Full-Length MS Protein Standard


Product Description:

Name UBE2B Full-Length MS Protein Standard
Cat# CPFL303306
Protein Nameubiquitin-conjugating enzyme E2B
SymbolUBE2B
SynonymsE2-17kDa; HHR6B; HR6B; RAD6B; UBC2
AccessionNM_003337
Cytogenetic5q31.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW17.1 kDa
Expression TrueORF CloneRC203306
DescriptionUBE2B Full-Length MS Protein Standard (NP_003328), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

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