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NDUFA12 Full-Length MS Protein Standard

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Product Description


NameNDUFA12 Full-Length MS Protein Standard
Cat#CPFL303265
Protein NameNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
SymbolNDUFA12
SynonymsB17.2; DAP13
AccessionNM_018838
Cytogenetic12q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNDUFA12 Full-Length MS Protein Standard (NP_061326), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.

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