CAPNS1 Full-Length MS Protein Standard


Product Description:

Name CAPNS1 Full-Length MS Protein Standard
Cat# CPFL303233
Protein Namecalpain, small subunit 1
SymbolCAPNS1
SynonymsCALPAIN4; CANP; CANPS; CAPN4; CDPS; CSS1
AccessionNM_001003962
Cytogenetic19q13.12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW28.8 kDa
Expression TrueORF CloneRC203233
DescriptionCAPNS1 Full-Length MS Protein Standard (NP_001003962), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

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