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EEF1D Full-Length MS Protein Standard

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Product Description


NameEEF1D Full-Length MS Protein Standard
Cat#CPFL303202
Protein Nameeukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
SymbolEEF1D
SynonymsEF-1D; EF1D; FP1047
AccessionNM_001960
Cytogenetic8q24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionEEF1D Full-Length MS Protein Standard (NP_001951), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.

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