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CEP19 Full-Length MS Protein Standard

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Product Description


NameCEP19 Full-Length MS Protein Standard
Cat#CPFL303186
Protein Namecentrosomal protein 19kDa
SymbolCEP19
SynonymsC3orf34; MOSPGF
AccessionNM_032898
Cytogenetic3q29
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionC3orf34 Full-Length MS Protein Standard (NP_116287), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2.

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