GSS Full-Length MS Protein Standard


Product Description:

Name GSS Full-Length MS Protein Standard
Cat# CPFL303174
Protein Nameglutathione synthetase
SymbolGSS
SynonymsGSHS; HEL-S-64p; HEL-S-88n
AccessionNM_000178
Cytogenetic20q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW52.2 kDa
Expression TrueORF CloneRC203174
DescriptionGSS Full-Length MS Protein Standard (NP_000169), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

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