PDE6D Full-Length MS Protein Standard


Product Description:

Name PDE6D Full-Length MS Protein Standard
Cat# CPFL303172
Protein Namephosphodiesterase 6D, cGMP-specific, rod, delta
SymbolPDE6D
SynonymsJBTS22; PDED
AccessionNM_002601
Cytogenetic2q35-q36
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW17.2 kDa
Expression TrueORF CloneRC203172
DescriptionPDE6D Full-Length MS Protein Standard (NP_002592), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

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