RNF2 Full-Length MS Protein Standard


Product Description:

Name RNF2 Full-Length MS Protein Standard
Cat# CPFL303089
Protein Namering finger protein 2
SymbolRNF2
SynonymsBAP-1; BAP1; DING; HIPI3; RING1B; RING2
AccessionNM_007212
Cytogenetic1q25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW37.5 kDa
Expression TrueORF CloneRC203089
DescriptionRNF2 Full-Length MS Protein Standard (NP_009143), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

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