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IRAK4 Full-Length MS Protein Standard

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Product Description


NameIRAK4 Full-Length MS Protein Standard
Cat#CPFL303041
Protein Nameinterleukin-1 receptor-associated kinase 4
SymbolIRAK4
SynonymsIPD1; IRAK-4; NY-REN-64; REN64
AccessionNM_016123
Cytogenetic12q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIRAK4 Full-Length MS Protein Standard (NP_057207), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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