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IRAK4 Full-Length MS Protein Standard


Product Description

NameIRAK4 Full-Length MS Protein Standard
Protein Nameinterleukin-1 receptor-associated kinase 4
SynonymsIPD1; IRAK-4; NY-REN-64; REN64
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW51.3 kDa
Expression TrueORF CloneRC203041
DescriptionIRAK4 Full-Length MS Protein Standard (NP_057207), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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