OPA3 Full-Length MS Protein Standard


Product Description:

Name OPA3 Full-Length MS Protein Standard
Cat# CPFL302959
Protein Nameoptic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
SymbolOPA3
SynonymsMGA3
AccessionNM_025136
Cytogenetic19q13.32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW19.8 kDa
Expression TrueORF CloneRC202959
DescriptionOPA3 Full-Length MS Protein Standard (NP_079412), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

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