RORA Full-Length MS Protein Standard


Product Description:

Name RORA Full-Length MS Protein Standard
Cat# CPFL302926
Protein NameRAR-related orphan receptor A
SymbolRORA
SynonymsNR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA
AccessionNM_134261
Cytogenetic15q22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW58.8 kDa
Expression TrueORF CloneRC202926
DescriptionRORA Full-Length MS Protein Standard (NP_599023), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.

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