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ACADM Full-Length MS Protein Standard

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Product Description


NameACADM Full-Length MS Protein Standard
Cat#CPFL302798
Protein Nameacyl-CoA dehydrogenase, C-4 to C-12 straight chain
SymbolACADM
SynonymsACAD1; MCAD; MCADH
AccessionNM_000016
Cytogenetic1p31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionACADM Full-Length MS Protein Standard (NP_000007), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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